Chatsworth is a neighborhood in the northwestern San Fernando Valley region of Los Angeles, California, United States.
The area was home to Native Americans, some of whom left caves containing rock art. Chatsworth was explored and colonized by the Spanish beginning in the 18th century. The land was part of a Spanish land grant, Rancho Ex-Mission San Fernando, in the 19th century, and after the United States took over the land following the Mexican–American War, it was the largest such grant in California. Settlement and development followed.